FACTS ABOUT NAD+ DEFICIENCY SYMPTOMS AND TREATMENT REVEALED

7c,d). Inhibition of glycolysis altered neither replication fork development nor the effects of NAD+ treatment, suggesting that glycolysis isn't a limiting aspect for NAD+-induced effects on DNA synthesis. Phenocopying the effect of BPTES, oligomycin rescued the inhibitory effect of NAD+ treatment on fork pace partially in HeLa and fully in U2OS ce